Module 2: Basic Pharmacology of Controlled Drugs and Substances
Some Basic Definitions
Pharmacotherapeutics is “the study of the therapeutic uses and effects of drugs”. Within this branch of pharmacy science are four important concepts (Poole Arcangelo, Peterson, 2016):
- Pharmacodynamics looks at the mechanism(s) of action or the effects of a drug on the human body.
- Pharmacokinetics looks at how the body affects the drug; specifically, how the drug is absorbed, metabolized, distributed and excreted.
- Pharmacogenetics examines how an individual’s genetic disposition may influence drug response, including both intended effects and adverse effects.
- Pharmacogenomics is a new field of “personalized medicine” that combines the study of pharmacology and genomics to help develop medications that can be modified or tailored to a patient’s specific genetic makeup.
- Poole Arcangelo, V., Petersen, A.M. & Wilbur (2016). Pharmacotherapeutics for advanced Practice: A practical approach. Wolters Kluwer: Philadelphia.